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The medication is administered once weekly via subcutaneous injection and is available in escalating doses ranging from 2.5 mg to 15 mg

In such a way that unoxidized fatty acids are rerouted toward the synthesis of diacylglycerol and ceramide, which in turn stimulate stress-induced protein kinases that inhibit insulin signaling (89, 90)

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Dilution of the acetylcysteine (see Preparation of Acetylcysteine for Oral Administration) minimizes the propensity of oral acetylcysteine to aggravate vomiting