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But, in severe cases, a hospital stay and further treatment may be required, such as an angiography (blocking off the bleeding artery), colonoscopy, or surgery

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Genetic deletion of the Fmr1 gene leads to a depletion of fragile X mental retardation protein (FMRP), resulting in the activation of the metabotropic glutamate receptors mGluR [331, 332]

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Acetic acid is another diluent you might see mentioned, but it's typically reserved for peptides that are less soluble in water