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Transferrin: structure, function and potential therapeutic actions

332 In addition, puerarin is known to improve MAFLD by inhibiting inflammation and ferroptosis

Even though these drugs have potential mechanism to prevent or treat DPN [77,78] and very low chance to induce side effects, but large-scale randomized controlled trials to show its efficacy on DPN are scarce

Key hallmarks and molecular mechanisms of aging In 2023, researchers integrated and elaborated on 12 characteristics of aging, 39 including genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis

Protein oxidation in muscle foods: a comprehensive review