(4) Conduct biomarker-enriched, mechanism-based clinical trials
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Lipid Metabolism & 3-AR Mechanism Heffernan et al., Endocrinology (2001) Heffernan and colleagues investigated the lipolytic effects of chronic AOD-9604 treatment using two complementary mouse models: diet-induced obese C57BL/6J mice and beta3 adrenergic receptor (3-AR) knockout mice
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[DOI] [PubMed] [Google Scholar] 23.Hong Y., Yan W., Chen S., Sun C.R., Zhang J.M