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For the majority of protocols particularly those involving sustained dosing, combination with GHRH analogs, or body composition endpoints ipamorelin's selectivity advantage outweighs GHRP-6's potency advantage

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[DOI] [PubMed] [Google Scholar] 87.Ionut V., Woolcott O.O., Mkrtchyan H.J., Stefanovski D., Kabir M., Iyer M.S., Liu H., Castro A.V.B., Wu Q., Broussard J.L., et al

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Impaired astrocyte function can result in decreased elimination of extracellular glutamate, leading to a reduced seizure threshold and an imbalance between neuronal excitation and inhibition (Bialer & White, 2010)