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Tolerability profile consistent with the incretin class, with gastrointestinal events most commonly reported in studies (e.g., nausea, diarrhoea, and constipation).

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Very little, if any, information is often available on the physiology, social status, and potential pre-exposure of the organism tested

In an analysis of more than 100 clinical trials of earlier anti-obesity medications, in studies lasting up to 76 weeks, drug-induced weight loss never exceeded more than nine pounds (4 kg)

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