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However, when recovery is inadequate, or exercise becomes chronic and excessive, this adaptive inflammation can become dysregulated, contributing to oxidative stress, immune suppression, muscle catabolism, and ultimately performance decline or overtraining syndrome [28, 29]

It is FDA-approved under the brand name Egrifta for HIV-associated lipodystrophy, a condition involving abnormal fat distribution

Similarly, gene-editing technologies like CRISPR offer potential breakthroughs but come with ethical dilemmas and safety concerns Doudna & Charpentier, Science , 2014

doi: 10.1074/jbc.M109.044065