For traumatic brain injury, the CAPTAIN program, summarized in a 2021 meta-analysis of two randomized trials and 185 patients, likewise reported modest benefit (Vester et al., 2021, pooled RCTs)
Dig Dis Sci 60:12151222 Lee S-W, Chang C-S (2021) Impact of overlapping functional gastrointestinal disorders on the quality of life in patients with gastroesophageal reflux disease
Metal-chelating properties of curcumin confirmed protection against Amyloid- aggregation and oxidative stress suppression, most probably by inhibiting the Fenton reaction (Baum and Ng 2004)
As shown in Table 1 , inhibitors or antagonists of these targets have shown good results in animals, such as CXCR3, CXCR4, CXCL10, CXCL12, and CXCL13, especially the antibody of CXCL10 (MDX-1100) has entered clinical trials (25) ( Figure 2 )
Determination of LongR3-IGF-I, R3-IGF-I, Des1-3 IGF-I and their metabolites in human plasma samples by means of LCMS