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While B12 deficiency is rare, some individuals may suffer from chronic health issues or autoimmune conditions, which prevents the body from properly storing or absorbing vitamin B12

Recovered clones were identified by sequencing, and representatives of all classes were expressed as described below

Thus, the Homology Modeling module of the Schrodinger Suite, with the Energy-based method and default settings, was used to generate a model of the full sequence between residues 101-494 of USP14 with the bound IU1-248 inhibitor

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