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Conversely, the overexpression of Parkin resulted in a reduction in the number of neurons lost in the motor cortex of TDP-43 model animals while also inhibiting the degenerative phenotype observed in hTDP-43 model animals (Hebron et al., 2014)

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282 Although the composition of human gut microbiota remains relatively stable from around age 3, gut microbiota undergoes the increase in diversity and altered proportions of composition

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