Over time, this extra fat can cause inflammation and harm the healthy parts of your liver
Simply put, its the fact that its currently illegal to obtain as well as to use for clinical studies, meaning it cannot be studied for its benefits or side effects
Due to the fact that changes in calcitriol levels alter plasma calcium and PTH levels it is not clear what the exact mode of action is for calcitriol relative to renal phosphate retention
The limitation: Monoclonal antibodies are expensive to produce, and while bimagrumab only needs to be taken once every four weeks, it needs to be administered intravenously, which has to happen in a medical facility
So, continuing to address those (with diet, therapy, etc.) in parallel is important