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(eds) Nitrite and Nitrate in Human Health and Disease

A structured roadmap for clinical translation From a translational perspective, microbiome-based stratification cannot be recommended as a routine clinical tool due to limited human evidence, methodological heterogeneity, absence of standardized analytical pipelines, and lack of validated microbial cut-offs

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Delayed gastric emptying also shifts the composition of gut bacteria, favoring fermentation-prone species that generate sulfur compounds

252 SAM supplementation reverses GSH depletion, reduces mitochondrial DNA damage, and ameliorates steatosis and hepatocyte necrosis in ethanol-fed models