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Headaches during initial use Headaches represent the second most commonly reported side effect

According to research conducted in 2008, the body only absorbs about 1.3% of a 1,000 mcg oral dose of B12

Phasing and lifestyle inputs are covered in Supporting Factors below

NNMT is heavily involved in the regulation of energy metabolism - its activity can promote fat storage and metabolic disorders

Although it cannot yet be determined whether vitamin B 12 deficiency plays a causal role in depression, it may be beneficial to screen for vitamin B 12 deficiency in older individuals as part of a medical evaluation for depression