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These findings are consistent with microdialysis studies showing that systemic doses of exendin-4 that attenuated cocaine-induced conditioned place preference and cocaine self-administration in mice also decreased cocaine-evoked dopamine release in the NAc 32 and dorsal striatum 36

It plays a key role in maintaining intracellular FA homeostasis by regulating the transcription of FAO-related enzymes in mitochondria and peroxisomes, and modulates cellular FA uptake through regulating the expression of CD36 and CPT1 (Lakhia et al., 2018)

Monitoring for adverse reactions is advised, and any concerns should be discussed with a healthcare provider

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