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However, there was a negative correlation of RBC glutathione with excretion of mercury at the 9th dose (r = -0.27), which suggests that mercury has an adverse effect on RBC glutathione, presumably by both causing it to be excreted from the body after the glutathione binds to mercury, and perhaps more importantly by inhibiting production of glutathione

This slowing of gastric emptying and possibly slower intestinal transit can contribute to constipation

10.3389/fimmu.2019.02247 4 Ait-OmarA.Monteiro-SepulvedaM.PoitouC.Le GallM.CotillardA.GiletJ.et al (2011)