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Timmers, S., Konings, E., Bilet, L., Houtkooper, R

The melanocortin arm raises a theoretical concern about chronic elevation of cortisol and blood pressure, but Russian clinical data at registered doses do not show this in practice

Zepbound is contraindicated in patients with a personal or family history of medullary thyroid carcinoma, in patients with Multiple Endocrine Neoplasia syndrome type 2, and in patients with known serious hypersensitivity to tirzepatide or any of the excipients in Zepbound

It also plays a critical role in maintaining cellular health by directly neutralising free radicals, as well as by maintaining the activity of vitamins C and E

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