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There are several neurotrophic agents capable of initiating such beneficial processes including NGF, BDNF, neurotrophin-3 and neurotrophin-4/5 [53-55]

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Chronic hypoxia promotes -syn phosphorylation at ser129 and abnormal aggregation in the mouse hippocampus Hyperphosphorylation and abnormal aggregation of -syn are closely related to neuronal degeneration

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