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doi: 10.1007/s00281-025-01038-9 94 BhattKOrlandoTMeuwisMALouisEStefanutoPHFocantJF

The American College of Physicians recommends setting realistic expectations: clinically meaningful weight loss is defined as 5% or greater reduction in baseline body weight

Research involving IBD patients has highlighted specific ferroptotic signatures, including disrupted iron homeostasis, depleted glutathione levels, and diminished GPX4 activity, which ultimately trigger an explosion of lipid reactive oxygen species (ROS) (Gao et al., 2021

Check out this handy matrix to understand which supplements have the most science on their side and which are mostly hype at this point

Amini A, Correa AM, Komaki R, Chang JY, Tsao AS, Roth JA, Swisher SG , Rice DC, Vaporciyan AA, Lin SH