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It requires a balanced approach that targets multiple factors like pigmentation, hydration, and protection

Andrographolide and 14-deoxy-11, 12-didehydroandrographolide inhibit cytochrome P450s in HepG2 hepatoma cells

Cumulative food intake of 52-week old female WT (n = 6) and KO mice (n = 7) (d)

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More recent systematic reviews and meta-analyses published between 2020 and 2022 have broadly confirmed this picture, reporting small, short-term reductions in body weight and body mass index, particularly in older adults and individuals with obesity or metabolic conditions, but with effect sizes that remain clinically modest