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Ipamorelin is notable because, unlike earlier GHRPs, it produces GH release without significantly elevating cortisol or prolactin

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Localized infusion of IGF-I results in skeletal muscle hypertrophy in rats

J Biol Chem 2016, 291:1159611607

Lilly and independent clinical observers have acknowledged this efficacy gap openly, framing Foundayo as an option for patients who cannot or will not use injectables, rather than a direct replacement for them