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Confocal laser endomicroscopy (CLE) is a more recent method to directly assess intestinal barrier function

There is also a serotonergic component

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Figure 2 4.3.2 Amplification of immune responses by released intracellular components following ferroptosis When ferroptosis leads to the rupture of chondrocytes or synovial cells, the oxidized lipid byproducts, iron ions, and damage-associated molecular patterns (DAMPs) that leak from these cells are detected by nearby immune cells

Philip Pape: 6:54 Confounding variables are the wild cards