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doi: 10.1001/jamainternmed.2018.2933 134 Perez-Montes DE OcaAPelliteroSPuig-DomingoM

The skin barrier problem This is the fundamental issue that makes current GLP-1 patches implausible as weight loss tools

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Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are a promising therapeutic option for people with arthritis and obesity or type 2 diabetes mellitus owing to their pleiotropic effects, including weight loss, improved survival and reduced risk of major cardiovascular and renal events

Effective tracking is essential when using semaglutide to ensure that weight loss targets fat rather than muscle