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Exenatide versus glibenclamide in patients with diabetes

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For both cohorts, animals were deeply anesthetised 90 min later (pentobarbital 100 mg/kg, i.p) and transcardially perfused with cold 0.1 M of phosphate buffer (PB) for 1.5 min followed by 4% of paraformaldehyde (PFA) in PB for 2.5 min

By activating two distinct but complementary pathways, the combination triggers a much more significant and controlled GH release in lab models than either peptide could ever manage on its own