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Additionally, it promoted the activation of the Akt/GSK-3 pathway, suggesting that IGF-1 LR3 therapy holds the potential to treat individuals with diabetic heart muscle-related issues [11]

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However, only 22% of the variation in MMA levels was explained by vitamin B12, estimated glomerular filtration rate, age, sex, and socioeconomic status, suggesting that other underlying disease was likely the reason for elevated MMA levels