They are promoted for youth repair, anti-aging, improved cognitive health and energy, even though there are no adequate data to support such claims in people
Efficacy and Safety of Once-Weekly Semaglutide Versus Exenatide ER in Subjects With Type 2 Diabetes (SUSTAIN 3): A 56-Week, Open-Label, Randomized Clinical Trial
Published 2024 Feb 19
This has not been confirmed in humans, but as a precaution, neither drug should be used by people with a personal or family history of medullary thyroid cancer (MTC) or a rare genetic condition called MEN2
The most commonly reported side effects of retatrutide in clinical trials are gastrointestinal, including nausea, vomiting, diarrhoea, constipation, and decreased appetite, consistent with other GLP-1-based therapies