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This immiscibility can be exploited for product precipitation: dissolving a product in DMF then adding hexane can crash out the product

The positive control used was topiroxostat, which showed an IC 50 of 17 nM, very close to compound 72 , the most active compound in the study (Figure 23)

Pycnogenol in health and disease: a systematic review [Cited 05th March 2026] World Health Organization

Each autoinjector contains the combination of: Front chamber (visible): 2.1 mg of atropine in 0.7 mL of sterile, colorless to yellow pyrogen-free solution

Based on the results, aNDBs could emerge as a novel weapon against bacterial infections to replace currently used antibiotics and antibiotic use approaches