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If therapy is interrupted, dose re-titration is typically recommended when restarting

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Zip8 A391t crohns disease-linked risk variant induces colonic metal ion dyshomeostasis, microbiome compositional shifts, and inflammation

doi: 10.3389/fnut.2026.1715574 Received 29 September 2025 Revised 30 December 2025 Accepted 09 January 2026 Published 12 February 2026 Volume 13 - 2026 Edited by Arpita Mukhopadhyay, St