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Capparelli C, Purwin TJ, Heilman SA, Chervoneva I, McCue PA, Berger AC, Davies MA , Gershenwald JE, Krepler C, Aplin AE

Rescue therapy with sulfasalazine prior to immunosuppressive or biological agents in ulcerative colitis poorly controlled with mesalazine]

Once toxicant burden is identified, the clinical roadmap shifts toward detoxification and immune modulation

Dimidi et al., 2019) since the generation of antimicrobial metabolites like organic acids, ethanol and bacteriocins reduce the risk of contamination with pathogenic microorganisms (Dimidi et al., 2019)

In addition, the observed significant decrease in serum levels of homocysteine showed acceptable compliance with supplementation in our participants