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mutans (Jain et al., 2015a)

FDA Permits Expanded Daraxonrasib Access in Previously Treated Metastatic PDAC Most recently, the FDA issued a safe to proceed letter for daraxonrasib, authorizing the initiation of an expanded access program for patients with previously treated metastatic pancreatic ductal adenocarcinoma

Another orally available, reversible, selective FASN inhibitor, TVB-3166, inhibits anchorage-dependent cell growth and induces apoptosis in PC cell lines and patient-derived xenografts through different downstream mechanisms [197]