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[20][21] While the aging pituitary remains responsive to GH, GHRH, and GH secretagogues, it is less responsive to stimuli such as exercise
If currently deferred due to active side effects or recent treatment initiation, you may become eligible once: You have been on a stable Wegovy dose for several months without significant adverse effects Your weight and overall health meet donation criteria (minimum weight of 50 kg, stable blood pressure, good venous access) Any obesity-related comorbidities are well-controlled Maintain contact with your local donation centre and ask about reassessment timelines
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However, the design of SURPASS-4 was based on the change in HbA 1c at 52 weeks, and not on MACE, as the primary outcome [21]
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