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Its active ingredient, semaglutide, acts on the appetite centres in your brain to help you feel fuller for longer, reduce hunger and lower food cravings

It has been posited that one potential mechanism underlying the phenomenon of weight regain or plateauing could be attributed to a decrease in leptin concentrations following initial weight reduction [38, 41]

Semaglutide base is the active ingredient in FDA-approved products (Ozempic, Wegovy, Rybelsus)

After taking semaglutide for 68 weeks, the average participant lost more than 15 percent of their body weight

Given the high prevalence of addiction and the limited availability of effective treatments for cocaine and stimulant use disorders, GLP-1-based therapies offer hope