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It is a logistics restructuring in real time , and ignoring it is no longer an option.

Reasons are assumed to be financial aspects, lack of the detailed toxicity studies, and of profound proofs for prolonged effects in humans

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Reproducibility remains one of the most important principles in scientific research

Moreover, the mitochondrial DNA content in tumor cells is lower than that in normal cells, which, together with the weakly acidic environment, prevents oxidative stress-induced cell death