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Vitamin B12 Essentials 2.1 Biochemical Roles and Neurological Importance Vitamin B12 (cobalamin) is indispensable for two biochemical pathways: Methionine Synthase : Converts homocysteine to methionine, fueling methylation reactions vital for DNA synthesis, neurotransmitter production (serotonin, dopamine), and myelin maintenance

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It is commonly prescribed for patients suffering from neuropathy, anemia, or nerve pain caused by diabetes, spinal cord injuries, or other neurological disorders

A combined deficiency is common in vegetarians and can mask or coexist with iron deficiency