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Semaglutides less common side effects Most of semaglutides known but less common side effects arise from studies looking at long-term use, often in patients and study participants whove used the drug for at least a year

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Absolute contraindications to phentermine, regardless of GLP-1 status: Uncontrolled hypertension History of coronary artery disease or heart failure Uncontrolled hyperthyroidism Glaucoma History of substance use disorder (phentermine is Schedule IV) Use within 14 days of MAO inhibitors Pregnancy or planning pregnancy Age over 65 (relative contraindication) The GLP-1 alone may still be appropriate in many of these scenarios

10.3389/fphar.2021.739615 21 ChenX.WeiW.LiY.HuangJ.CiX

The most common ones include mild gastrointestinal symptoms such as nausea, vomiting, and diarrhea, which typically subside over time