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Studies have shown that Tartary buckwheat flavonoids have protective effects on vascular dysfunction and liver injury induced by TMAO in mice, mainly through antioxidant stress, but the specific mechanism remains unclear (93)

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It works by inhibiting tyrosinase but it can be irritating, and if overused, it can cause rebound worsening of pigmentation

In endothelial progenitor cells (EPC) derived from human peripheral blood mononuclear cells, high glucose conditions downregulate GLP-1-R and sirtuin 1 ( SIRT1 ) expression, leading to impaired cell functions and increased apoptosis via elevated acetylated p53 levels

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