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The goal is always to match the right intervention to the right patient at the right time not to apply a protocol indiscriminately

Instead, it is more appropriate to envision metabolic plasticity regarding uptake of alternative metabolic substrates and promotion of metabolic rewiring as a built-in feature that has evolved to allow cancer cells to constantly adapt to changing intracellular- and extracellular metabolic conditions 2

Edick et al., 2020)

The approved weight-management formulation, Wegovy, starts at 0.25 mg weekly and titrates to a 2.4 mg maintenance dose over 16-20 weeks to reduce gastrointestinal side effects

T.WebsterL.HowardJ.DoyleP.et al