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Its structure incorporates several non-natural amino acid modifications that enhance receptor binding affinity and metabolic stability compared to endogenous ghrelin
Beyond the Primary Endpoint: Cardiometabolic and Body-Composition Signals Both compounds act on a hormonal axis with wide-ranging metabolic effects, so it is reasonable to ask what happens beyond the headline endpoint
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Antibodies used were rabbit anti-ACSL4 (1:1000) (ThermoFisher, #PA527137, RRID: AB_2544613), anti-GAPDH (1:1000) (Cell Signaling, #5174, RRID: AB_10622025), and anti-GPX4 (1:1000) (ThermoFisher, #MA532827, RRID: AB_2810103)
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