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Finally, a third enzyme located within the mitochondrial matrix, Carnitine Palmitoyltransferase 2 (CPT2), reverses the initial reaction

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This finding suggests that decreased DPP4 levels may be associated with the altered immune regulation in SLE, potentially contributing to its pathogenesis

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Unless the context otherwise requires, reference in this Annual Report to the terms Septerna, the Company, we, us, our, and similar designations refer to Septerna, Inc

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When injected with precision into the targeted muscle, the muscle relaxes and the overlying skin smooths because the repeated muscle contraction that creates dynamic wrinkles (frowning, forehead-raising, squinting) is reduced

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