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Upon the induction of the maternal immune system, activated microglia releases inflammatory cytokines to amplify the inflammatory response and recruit immune cells to the site of inflammation [50]

Alpha-smooth muscle actin expression upregulates fibroblast contractile activity

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Locking the backbone into a ring reduces that conformational freedom, so a far larger proportion of molecules present the right shape at any moment, which raises apparent potency without changing the recognition sequence at all

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