STAT5-glucocorticoid receptor interaction and MTF-1 regulate the expression of ZnT2 (Slc30a2) in pancreatic acinar cells
Hypoglycemia Care: Ensure enough nutritional support around use times Consider dose reduction if hypoglycemia occurs Use glucose tracking protocols Have glucose use available if needed Injection Site Reaction Care: Rotate injection sites systematically Use proper injection technique Consider lower level solutions Apply cold compress if major reaction occurs Fluid Retention Care: Track body weight and signs of edema Consider dose reduction if major retention occurs Ensure enough hydration Track electrolyte balance Research Ethics and Informed Consent All research involving IGF1 LR3 should be conducted with appropriate ethical oversight and informed consent procedures
Hanmi is pursuing expansion of efpeglenatides indications beyond obesity into diabetes, targeting obesity approval in the second half of 2026 and diabetes indications in 2028
And please, when you go, and yourself too, if you have any thoughts about policy issues, economic issues that are impacting patients, if you have questions, or you hear things, let us know
We assessed the GLP-1R agonists (exenatide, liraglutide, dulaglutide, semaglutide) and the dual GIPR/GLP-1R co-agonist tirzepatide as separate classes
