Medications like semaglutide (sold as Ozempic and Wegovy) and newer oral options like orforglipron work by mimicking a gut hormone called glucagon-like peptide 1, which signals to the brain that you're full
Sjstrm L, Narbro K, Sjstrm CD, Karason K, Larsson B, Wedel H, et al
You may be at a higher risk of dehydration if you: take medicines to lower your blood pressure, including water pills (diuretics) are on a low salt diet have kidney problems are 65 years of age or older Talk to your healthcare provider about what you can do to prevent dehydration including how much fluid you should drink on a daily basis
These studies have focused on how the peptide interacts with hormone receptors involved in appetite regulation, glucose metabolism, and energy use
The medication can support that effort, but it does not replace it, and we will not pretend otherwise