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In this context, murine studies have shown that sweet taste receptors (TAS1R2 and TAS1R3) are predominantly expressed in the hypothalamus and brainstem, whereas bitter receptors (TAS2R116, TAS2R118, TAS2R138, TAS2R104) are mainly expressed in the arcuate nucleus, ventromedial hypothalamus, dorsomedial hypothalamus, and nucleus of the solitary tract (120, 121)

Serious side effects of Wegovy are rare but can occur

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Jan 2019;38(1):95-99

Methodology The study included a random nationwide sample (n=655) of patients treated with branded semaglutide (Wegovy or Ozempic) through Ro's platform who persisted with treatment and reported their weight at 68 weeks (14 days)