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Making time to go to the bathroom at the same time every day (such as first thing in the morning, or after meals) trains our migrating motor complex (which moves food through our intestines) that now is the time for a bowel movement

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Lyophilized peptides from the HpH RP fractionation (20 concatenated fractions) were resolubilized in 35 L of 0.1% formic acid (FA) and loaded onto a 20 cm analytical column (100-m inner diameter) packed with ReproSilPur C18 AQ 1.9 m reversed-phase material

IC was assessed at short (minutes) (IC rats, IC + RL rats) or more prolonged (3- and 10-d) intervals (IC + OB rats)