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Conversely, the ER stress inhibitor (4-PBA) did not mitigate PFOS-phosphorylated ERK1/2 levels at 1 h of PFOS treatment in RTCs, but it reduced the level of LC3BII (an autophagy biomarker) at 24 h of PFOS treatment in RTCs (Fig

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One study reported that dietary fiber did not provide significant relief for patients with severe constipation and only provided relief for patients with mild constipation (33)