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lifelong supplementation is required (26)

While both peptides share the goal of enhancing recovery, their mechanisms of action, benefits, and applications differ in meaningful ways

An amide derivative 13d (Ca2+ flux IC50 = 188 nM, [brain]/[plasma] = 0.97 @ 8 h in rat), for example, showed a 10% decrease in 24-hour food intake in rats, and over 5% body weight reduction after 14-day oral treatment in diet-induced obese (DIO) mice (180)

It also improved cerebral oxidative metabolism and neurological outcomes in rats following cortical contusion injury (Fukushima et al., 2009

These are meaningfully different clinical situations