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Obesity is associated with low-grade systemic inflammation, characterized by increased levels of inflammatory markers such as Toll-like receptor 4 (TLR4), tumor necrosis factor-alpha (TNF-), IL-6, IL-1 [36], IL 17, leptin [37], and resistin [38]

While structurally distinct from GLP-1 analogs, GLP-3 R is being investigated for its potential interactions with GLP receptor pathways and its role in energy balance, insulin sensitivity, and weight management

PMID: 29487568

Notably, insomnia prevails even in well-compensated cirrhosis stages and is not linked to neuropsychiatric impairment