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However, evidence on longer-term outcomes, side effects, and potential conflicts of interest remains limited or uncertain

You feel full sooner and stay full longer

While this contributes to feelings of fullness which helps with weight loss, it can also leave patients with a lasting feeling of fullness, bloating, and nausea, especially if portions are too large or if meals are high in fat

Summary: Retatrutide has not been proven safe for women, as it remains an unlicensed investigational medicine in the UK with limited sex-specific safety data from early-phase trials only

Slow vs fast titration compared at matched final maintenance dose for both 4 mg and 8 mg cohorts