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Preclinical data suggests this effect persists with chronic treatment

By activating GLP-1 receptors, retatrutide slows gastric emptying the rate at which food moves from the stomach into the small intestine

Caturano A, DAngelo M, Mormone A, Russo V, Mollica MP, Salvatore T, et al

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The authors said future research will explore how patient characteristics, specific medications, and timing of therapy influence treatment trajectories, with the goal of informing more personalized and sustainable approaches to obesity care