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There is some evidence that these individuals exhibit a higher risk of cancer

doi: 10.1046/j.1526-4610.2003.03006.x [DOI] [PubMed] [Google Scholar] 17.Whyte CA, Tepper SJ

More importantly, the reperfusion or restoration of blood flow after ischemia can also induce the increase of ROS and lipid peroxidation, leading to tissue neuronal damage and worsening of the inflammatory response