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Overview GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper complex) is an endogenous tripeptide that binds copper(II) ions with high affinity and is present in human plasma at concentrations that decline markedly with age from roughly 200 ng/mL at age 20 to approximately 80 ng/mL by age 60

The brain: Appetite and beyond GLP-1 signals travel from the gut to the brain via the bloodstream and the vagus nerve

However, nearly all data come from lab and animal studies rather than controlled human trials, so claims about systemic hormone changes warrant caution

A 1 mg dose then requires 6 units on a 100-unit insulin syringe (0.06 mL)

Further work is required to resolve this issue